It was demolished at some point after the mid-twentieth century, and today Lisle House exists primarily as a ghost in the architectural record: a measured drawing in the 1913 Georgian Society Records, a sketch from 1904 by T. J. Westropp, and a handful of scholarly references that collectively mourn something genuinely unusual. What made it unusual was in the brickwork. The architectural historian Maurice Craig noted that the window-heads displayed undulated arrises, a refined finishing technique associated with the Thames Valley and eastern England, in which bricks are rubbed and gauged to produce sharp, precise edges and subtle curves. It was a fashionable import, and its appearance in Crumlin placed the house in rare company, Craig drawing a parallel with Jigginstown in Co. Kildare.

The house's origins were layered in the way that Dublin's older villages often are. The site may have stood on or incorporated the earlier manor house of Crumlin, which in the first half of the seventeenth century was the residence of Sir Patrick Fox, Clerk of the Council, whose widow and family were caught up in the turbulence of the 1641 Rebellion. By the latter half of that century the Crumlin lands had passed to Major Joseph Deane, and it was his grandson, Joseph Deane the younger, who built the red-brick house that would eventually bear the Lisle name. The younger Deane rose to become Chief Baron of the Exchequer in Ireland, entering that office in 1714 on the accession of George I, though he died in May 1715, barely a year into the role. Around 1725, roughly a decade after his death, the house was advertised for sale, described at the time as a handsome new-fashioned residence. It was bought into a Cork family when John Lysaght, later the 1st Lord Lisle, married Catherine Deane, one of the Chief Baron's daughters and co-heiresses. The Lysaghts held seats across Munster, from Mountnorth to Curraglass near Mallow, but Crumlin became part of their portfolio, and the house took the name by which it is now recorded.

There is nothing to visit. Westropp's 1904 drawing, which for many years was incorrectly labelled as depicting the nearby Crumlin House, actually shows Lisle House as an eight-bay, two-storey structure with a central pedimented breakfront, a doorway beneath the pediment, and an oculus at its apex. A pedimented breakfront is a central section of a facade that projects slightly forward and is crowned with a triangular gable, giving the building a formal, classical emphasis. The tall rectangular chimney stacks visible to the rear in Westropp's sketch are what prompted speculation about an older structure beneath. Rocque's map of 1760 places the house approximately 430 metres to the north-west of Crumlin House, which at least fixes its general location. Craig, writing in 1976, recalled having seen the building still substantially standing around 1950. What happened between then and its eventual demolition is not, on the current record, precisely known.